Why are some adolescents stopping orlistat early in treatment?

Adolescents may stop orlistat early in treatment primarily due to the gastrointestinal side effects that are often associated with its use, particularly flatulence. Orlistat functions by inhibiting the absorption of dietary fats, which can lead to an increase in undigested fat passing through the intestines. As a result, many users experience frequent flatulence, which can be uncomfortable and socially embarrassing. This discomfort can significantly impact the individual's willingness to continue the medication, especially in adolescents who may be more sensitive to social situations and peer perceptions.

The other side effects, while they can occur, tend to be less commonly reported as primary reasons for discontinuation compared to the gastrointestinal discomfort experienced from flatulence, making it a more prominent concern in this demographic.